Principal Investigator

Jennifer A. Doudna
Li Ka Shing Chancellor's Chair in Biomedical and Health Sciences Howard Hughes Medical Institute Investigator Professor, Molecular & Cell Biology; Professor, Chemistry
708A Stanley Hall
Voice: 510-643-0225
Fax: 510-643-0080
Jennifer A. Doudna
Principal Investigator

Dr. Jennifer Doudna is a member of the departments of Molecular and Cell Biology and Chemistry at UC Berkeley, the Howard Hughes Medical Institute, and Lawrence Berkeley National Lab, along with the National Academy of Sciences, and the American Academy of Arts and Sciences.

Biographical Highlights:

Administrative Assistant

Molly Jorgensen
Voice: 510-643-0113
Fax: 510-643-0080

Lab Safety Officer

Chun-Hao Huang
731 Stanley Hall
Chun-Hao Huang
Lab Safety Officer

Hepatitis C virus (HCV), which infects 170 million people globally and leads to liver cancer, employs an unusual strategy to hijack host ribosomal subunits and translation initiation factors to synthesize viral proteins using internal ribosome entry site (IRES) RNA. Although this mechanism play an important role in viral life cycle, a detailed understanding of the interplay between host immunity and virus infection will be needed to identify and characterize unrevealed RNA-mediated translational regulation. To this end, my research goal is to apply cutting edge genomic, molecular, biochemical, and animal modeling approaches to: 1) determine IRES RNA mediated mechanisms for controlling HCV translation, and 2) study the host cellular responses to HCV translation. Successful completion of the proposed work will provide a deep understanding of virus-host translational interactions during tumorigenesis and lead to developing more effective cancer prevention and therapies.

Graduate Programs

We accept graduate students primarily from three UC Berkeley graduate programs:

If you are interested in graduate research in our lab, you should first contact those programs for application materials and additional information.