Sensitive detection of nucleotides

We have shown proof-of-concept experiments demonstrating the possibility of using CRISPR-Cas systems as sensitive assays to diagnose the presence of viral pathogens such as HPV (Chen et al, 2018). This technology is being developed for clinical use.

Read more about how techniques in the Doudna lab lead to this novel platform, and how this fits in to the rest of our research, in the “Structure and Mechanism” research area.